Hybrid Chitosan-ZnO reinforced ultra-high molecular weight polyethylene (UHMWPE) was prepared using hydraulic hot press. The effect of ZnO contents (10, 20, 30 wt.%) and chitosan contents (1, 2, 3 wt.%) on the mechanical and morphology properties of UHMWPE/ZnO and UHMWPE/Chitosan-ZnO reinforced composites were successfully investigated. The compound with addition of 10 wt.% of ZnO recorded an increase in tensile properties. Further studies with addition of Chitosan found that hybrid composites recorded better mechanical properties than UHMWPE/ZnO composites, with UHMWPE/ZnO + 3 wt.% Chitosan composite attained comparable tensile strength, stiffness, and hardness to virgin UHMWPE. From fractographic analysis using scanning electron microscope (SEM), the absence of holes at the tensile fracture surface had verified the better tensile strength recorded by UHMWPE/ZnO + 3 wt.% Chitosan composite. Overall, the UHMWPE/ZnO + 3 wt.% Chitosan hybrid reinforced composite recorded comparable tensile properties to virgin UHMWPE.