Equation oriented modelling of chemical processes can be done using different modelling environments such as Matlab, Fortran and gPROMS. However, it is a time consuming process and require a lot of programing effort. Since the modelling is done using their own programming languages, it has the poor readability. Thus, users prone to make the mistakes during code writing and error identification will be tedious. In this study, a new modelling environment called MOSAIC will be used for modelling of chemical processes. MOSAIC is a web based modelling software and it introduces a novel approach to equation based modelling. To demonstrate its capability, a reactive distillation (RD) model is used as a case study. The RD results from the modelling work in MOSAIC fitted well with the results found in literature. Using MOSAIC, the modelling effort is possible even without the knowledge of programming languages. In addition, it is fond to be less errors and saves time. A comparison with other modelling software is also presented indicate the advantages and disadvantages of MOSAIC. Such assessment is important to help in deciding to use MOSAIC for any modelling works.